The Fall 2024 BACPAC meeting was held on November 20–21 in Chapel Hill, North Carolina, with virtual participation via Zoom. REACH investigators shared updates on their work in clinical phenotyping, modeling, biomechanics, and imaging, and contributed to a panel discussion titled "Breaking Down Large Datasets" led by Dr. Conor O'Neill, along with Dr. Gina McKernan and Dr. Leming Zhou from the University of Pittsburgh.
The second day concluded with a summary of collected BACPAC data and discussions on refining its use for future analyses, with highlights to the BEST Trial Study, recognized as the consortium’s largest collaborative initiative.
Looking ahead, these topics will set the stage for continued discussion at the Spring 2025 BACPAC Meeting, scheduled for April 22–23.
The following presentations were made by REACH investigators:
BACPAC Project Updates and Results:
Clinical Phenotyping
Association between MRI findings and inflammatory back pain symptoms (Conor O'Neill, MD)
Modeling
Knowledge augmented causal discovery: application in chronic low back pain through large language models and knowledge graphs (Abel Torres-Espin, PhD)
Predictive Modeling for cLBP Patient Outcomes (Thomas Peterson, PhD)
Leverage emerging technologies to expand the scope and depth of whole person health data via participants' systematically detailed stories of living with cLBP (Anthony Hunt, PhD)
Biomechanics
Spatial distribution patterns of multifidus fat infiltration and mechanistic relationships with chronic low back pain (Jeannie Bailey, PhD)
Imaging
Event-based modeling of MRI imaging features (Terence McSweeney, PhD)
Brain networks predict sensation patterns on Body Maps (Andrew Bishara, MD; Jennifer Cummings, PhD Candidate)
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